Topiramate is a medication primarily used to treat seizures and prevent migraines. It is also used off-label to aid in weight loss by reducing appetite and controlling cravings.

Topiramate modulates the activity of neurotransmitters in the brain, enhancing gamma-aminobutyric acid (GABA) activity while inhibiting glutamate activity. This dual action stabilizes brain activity, reduces hunger signals, and helps prevent binge-eating behaviors.

When taking topiramate, expect a reduction in appetite and cravings, leading to weight loss. You may also notice improvements in mood and a decrease in binge-eating episodes. Common side effects such as tingling in the hands and feet, dizziness, and changes in taste may occur but often subside as your body adjusts to the medication.